7/31/2023 0 Comments C reactive protein quant![]() ![]() The antiserum contains a specific substance that is able to detect the CRP. ![]() However, the HS CRP can reflect many things in lupus patients besides lupus activity and/or oneâs risk of heart attack.įor the HS CRP test, blood is taken from a vein in your arm and mixed with a substance called an antiserum. The high sensitivity CRP is important because studies have shown that lupus patients have higher levels of atherosclerosis than the general population. A high sensitivity test (high sensitivity C-reactive protein, or HS CRP) is used to evaluate this risk, because the level of CRP in the blood is low. In apparently healthy individuals, studies have shown that C-reactive protein (CRP) can be an indicator of the risk of cardiovascular disease (CVD), since certain types of CVD, namely atherosclerosis, are known to involve inflammation. High Sensitivity C-Reactive Protein (HS CRP) An elevated CRP can also be seen after someone has a heart attack, surgical procedure, or infection. It is important to realize, though, that a low CRP value does not necessarily mean that an individual is experiencing no inflammation a low CRP can be seen in lupus patients with active inflammation. However, the amount of CRP can give an idea as to the degree of inflammation your body is experiencing, and it is used by doctors in lupus treatment to monitor flares and to assess how well your medications are working. The CRP is non-specific, meaning it cannot give your doctor information about where inflammation is occurring in your body. CRP plays a part in your immune response by interacting with your bodyâs complement system. However, CRP usually changes more rapidly than ESR because it is made by the liver and secreted hours after the beginning of infection or inflammation. We raise the possibility that this particular low concentration might represent a physiological status and is not necessarily a result of the improved general health profile per se.Like the erythrocyte sedimentation rate, the C-reactive protein (CRP) test measures inflammation. After calculating the concentration of this biomarker following multiple adjustments, the individuals with very low CRP remained with a very low value despite the multiplicity of the adjustments. In addition, these individuals had less atherothrombotic risk factors, except for smoking habits which were as frequent as in those of individuals with a higher hs-CRP concentration. They were found to be significantly younger and lean, had an improved lipid profile and an attenuated acute-phase response in terms of lower erythrocyte sedimentation rate and fibrinogen concentration as well as white blood cell count. One hundred and sixty (2.4%) individuals out of the above-mentioned cohort presented hs-CRP concentrations of ![]()
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